β-CUBE
The β-CUBE is our high-performance preclinical PET imager.
Sub-millimeter image resolution is achieved through the combination of monolithic scintillators, the latest photon counting technology and GPU-based event positioning and iterative image reconstruction. The 5-ring configuration ensures best-in-class sensitivity over a field-of-view adequate for whole-body mouse and rat imaging at high count rate. In-house hardware allows for dynamic and gated studies. Intuitive and wireless acquisition software combined with our multimodal small animal bed allow for easy and modular multimodal imaging along with the γ-CUBE (SPECT) and X-CUBE (CT).
Gallery
Rat - PET - 10.29 MBq 18F-NaF MIP
Rat - PET - 10.95 MBq 18F-FDG MIP
Mouse - PET/CT - 11C-raclopride PET/CT
18F-NaF mouse bone scan
Whole-body 18F-FDG mouse scan
Mouse heart scanned with 18F-FDG - PET/CT
Mouse maximal heart uptake 18F-FDG
Full body rat (200g) with metastases, 18F-FDG, 3 bed positions; 10 min/bed position
10.67 MBq [18F]FDG
Rat - PET - coregistered with MR - 11C-raclopride 5.7 Mbq
Glioblastoma rat model, 8.89 MBq 18F-FDG @ start acquisition. 10 minute scan
Dynamic PET acquisition after injection of 4.44 MBq [18F]-FCA, a bile acid analogue (Stef de Lombaerde et al., 2016, Plos One).
Left: PET-MR; middle: gadolinium enhanced T1 weighted MRI; right: PET time activity curves
Rat - PET/CT - 10.11 MBq 18F-NaF - 15 min PET acquisition (5 min/bed position) MIP
FDG mouse, 1.85 MBq,
10 min PET acquisition
NaF bone scan (1.84 MBq injected), 10 minute scan
Mouse Hotel NaF - 4 mice of 18g
18F-FDG rat brain glioblastoma
Cu64 GNP mouse
NaF Zebra fish
[18F]CF4 to image lung ventilation
Biodistribution of [18F]-labeled carbondots
Cardiac gated PET with [18F]FDG
Compare the cubes
γ-CUBE
GP mouse protocol
Field Of View
12mm x 30mmResolution
< 0,6mm*Sensitivity
0,12%Reconstruction Code
MLEMWeight
75kgX-CUBE
Field Of View
35mm x 63mmResolution
0,05mmSensitivity
-Reconstruction Code
FDK, ISRAWeight
106kgβ-CUBE
Field Of View
130mm x 72mmResolution
0,85mm**Sensitivity
12,6%Reconstruction Code
FBP, 3D MLEM, 3D OSEMWeight
78kg