61Cu-PSMA-Targeted PET for Prostate Cancer: From Radiotracer Development to First-in-Human Imaging

2024-09-03
Bernabeau et al.
Pubmed

Results

The first figure shows the dynamic PET/CT scans of [61Cu] Cu-DOTAGA-PSMA-I&T and [61Cu]Cu-NODAGA-PSMA-I&T, respectively, from 0 to 1 h after injection. Time–activity curves showed uptake in the tumor within minutes after injection, an uptake peak of approximately 30 minutes, and stability remaining for up to 60 minutes.

The second figure compares PET/CT imaging of an early versus a late time point (one vs. four h after injection). [61Cu]Cu-DOTAGA-PSMA-I&T accumulated mainly in the liver, kidneys, intestine, and gallbladder.

Any info about the facts and figures?
PET
- β-CUBE
FULL SPEC SHEET