Highest combined sensitivity & resolution with the smallest footprint

SPATIAL RESOLUTION
< 850 µm
SENSITIVITY
> 12%

PET
β-CUBE

The β-CUBE is our high-performance preclinical PET imager.

Sub-millimeter image resolution is achieved through the combination of monolithic scintillators, the latest photon counting technology and GPU-based event positioning, and iterative image reconstruction. The 5-ring configuration ensures best-in-class sensitivity over a field of view that is adequate for whole-body mouse and rat imaging at a high count rate. In-house hardware enables dynamic and gated studies. Intuitive, wireless acquisition software, combined with our multimodal small-animal bed, enables easy and modular multimodal imaging when used along with the γ-CUBE (SPECT) and X-CUBE (CT).

β-CUBE/PET
Dimensions (LxHxW) 54x56x54 cm
Weight 77,5 kg
Axial FOV (mouse/rat) 130 mm
Transaxial FOV (mouse/rat) 72 mm
Resolution 850 µm
Peak Sensitivity > 12 %
Energy Resolution 12,6 %
Crystal/Detector Technology LYSO cont./SiPM
Reconstruction Algorithms 3D MLEM
Lowest animal radiation dose -

SPATIAL RESOLUTION
50 µm
DOSE
< 4 mGy

CT
X-CUBE

The X-CUBE is our high throughput CT “work horse”. It allows for fast whole body mouse and rat CT imaging at extremely low dose and excellent soft tissue contrast.

The light weight of this self-shielded imaging unit makes it a truly mobile in-vivo scanner. Advanced workflows, such as gated and dynamic contrast enhanced imaging, can be achieved in a functional and integrated setup. Our iterative reconstruction techniques are available in standard as well as in expert user mode. Intuitive, wireless acquisition software, combined with our multimodal small-animal bed, enables easy and modular multimodal imaging when used along with the γ-CUBE (SPECT) and β-CUBE (PET).

X-CUBE/CT
Dimensions (LxHxW) 54x56x70 cm
Weight 106 kg
Axial FOV (mouse/rat) 37 mm / 1 bed position
Transaxial FOV (mouse/rat) 65 mm
Resolution 50 μm
Peak Sensitivity -
Energy Resolution -
Crystal/Detector Technology 14 bit CMOS, 75 μm
Reconstruction Algorithms FDK, ISRA
Lowest animal radiation dose < 4 mGy

SPATIAL RESOLUTION
< 0,5 mm
SENSITIVITY
1,2%

SPECT
γ-CUBE

The γ-CUBE is our high-sensitivity, high-resolution SPECT imager for whole body mouse and rat imaging.

Patented lofthole technology and laser sintered collimators, combined with high-resolution detectors, result in a high-end true benchtop imager.  Image reconstruction software, developed in-house, guarantees fast imaging and excellent image quality. All common SPECT-labeled therapeutic and diagnostic imaging tracers can be imaged. Intuitive, wireless acquisition software, combined with our multimodal small-animal bed, enables easy and modular multimodal imaging when used along with the X-CUBE (CT) and β-CUBE (PET).

γ-CUBE/SPECT
Dimensions (LxHxW) 54x56x54 cm
Weight 78 kg
Axial FOV (mouse/rat) 6 mm (m) / 15 mm (r)
Transaxial FOV (mouse/rat) 35 / 60 mm
Resolution < 500 µm (m) / < 1mm (r)
Peak Sensitivity 1,2 / 0,12 / 0,05 %
Energy Resolution < 11 %
Crystal/Detector Technology Nal cont./SiPM
Reconstruction Algorithms 3D MLEM
Lowest animal radiation dose -

MOLECUBES around the world

PET/CT at UPENN, Philadelphia, USA
MOLECUBES has installed a PET/CT full body rat and mice set-up at the University of Pennsylvania (UPENN) at the lab of Prof. Joel Karp.
PET/CT at Universitätsklinikum Essen, Germany
MOLECUBES installed its PET/CT full body rat and mouse benchtop system at Universitätsklinikum Essen, Germany in the Preclinical Imaging Laboratory of Prof. Ken Herrmann.
PET/PET/SPECT/CT at KULEUVEN
The Molecular Small Animal Imaging Center core facility (MoSAIC) at KU Leuven has significantly expanded its preclinical PET capability with a PET PET CT setup from MOLECUBES
SPECT/CT at Uniklinik RWTH Aachen, Germany
MOLECUBES installed a SPECT/CT full body rat and mouse benchtop combination at the Uniklinik RWTH Aachen, Germany in the preclinical imaging laboratory of Prof. Felix Mottaghy
PET/SPECT/CT at University of Chicago, USA
MOLECUBES installed a PET/SPECT/CT whole-body rat and mouse benchtop imaging solution at the University of Chicago, USA, in the Integrated Small Animal Imaging Research Resource (iSAIRR) core facility.