The Molecular Small Animal Imaging Center core facility (MoSAIC) at KU Leuven has significantly expanded its preclinical PET capability with a PET PET CT setup from MOLECUBES. The combination of 2 β-CUBEs with 1 X-CUBE will enable unprecedented throughput whilst maintaining best-in-class image quality. The addition of this platform to the existing state-of-the-art in vivo imaging infrastructure, in combination with the extensive expertise for the non-invasive and longitudinal assessment of preclinical disease and therapy models at MoSAIC, will accelerate translational imaging research at KU Leuven – ensuring KU Leuven remains at the forefront of preclinical imaging and breakthrough research.