Customer webinar: Optimizing preclinical brain PET studies using data-driven normalization.

By prof. dr. Christian Vanhove – Infinity Lab – Ghent University – December 2021

Positron Emission Tomography (PET) is a powerful tool for the non-invasive evaluation and quantification of brain function. One of the easily accessible radiotracers in PET imaging is 18F-FDG and is used to evaluate global and regional glucose consumption in the brain in order to diagnose and to follow up neurological disorders. However, brain glucose uptake is subject-dependent because of many physiological factors like blood glucose level, anaesthesia, gender, etc. Therefore, data normalisation can improve quantification results and lower the standard deviations. In this webinar, prof. dr. Christian Vanhove will discuss how data-driven intensity normalization can improve and standardise 18F-FDG voxel-based brain analysis and quantification.